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Berberine (chloride)
$30 – $50
Products Details
Product Description
– Berberine chloride is an alkaloid that acts as an antibiotic. Berberine chloride induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase. Antineoplastic properties[1].
Web ID
– HY-18258
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C20H18ClNO4
Citations
– Aquacult Nutr. 14 Jul 2022.|Biochem Pharmacol. 2021 Apr 27;114576.|Mech Ageing Dev. 2020 Oct;191:111347.|Oncologie. 2023 Mar 10.|Phytomedicine. 2023 Jul 17, 154962.|Research Square Preprint. 2021 May.|Research Square Print. 2022 Aug.|Acta Pharmacol Sin. 2022 Aug 10.|Aquaculture. 15 May 2022, 738055.|Biol Pharm Bull. 2022 Jul 20.|BMC Pharmacol Toxicol. 2023 May 11;24(1):29.|Evid-Based Compl Alt. 2021 May 4.|Exp Cell Res. 2020 Aug 1;393(1):112054.|Food Chem Toxicol. 2023 Mar 25;113743.|Gene. 2022 Jan 10;146171.|Int J Nanomedicine. 2023 Jul 31.|J Bone Miner Metab. 2021 Apr 8.|J Ethnopharmacol. 8 November 2021, 114786.|J Pharm Pharmacol. 2022 May 31;rgac026.|JCI Insight. 2023 Jul 24;8(14):e166306.|Mol Med Rep. 2023 Jan;27(1):17.|Research Square Preprint. 2021 Jun.|Research Square Preprint. 2021 Sep.|Sci Rep. 2022 Oct 17;12(1):17350.|SSRN. 2023 Jan 27.|Cardiovasc Drugs Ther. 2021 Jul 28.|J Appl Microbiol. 2021 Apr;130(4):1154-1172.|Microbiol Spectr. 2023 Sep 25;e0217023.
References
– [1]Cai Y, et al. Berberine inhibits the growth of human colorectal adenocarcinoma in vitro and in vivo. J Nat Med. 2014 Jan;68(1):53-62.
CAS Number
– 633-65-8
Molecular Weight
– 371.81
Compound Purity
– 99.66
SMILES
– COC1=C(OC)C2=C[N+]3=C(C(C(CC3)=C4)=CC5=C4OCO5)C=C2C=C1.[Cl-]
Clinical Information
– Launched
Research Area
– Cancer
Solubility
– DMSO : 12.5 mg/mL (ultrasonic)|H2O : < 0.1 mg/mL (ultrasonic)
Target
– Antibiotic;Autophagy;Bacterial;Endogenous Metabolite;Parasite;Reactive Oxygen Species;Topoisomerase
Pathway
– Anti-infection;Autophagy;Cell Cycle/DNA Damage;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
