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AZ506
$360 – $2,980
Products Details
Product Description
– AZ506 is a potent SMYD2 inhibitor with an IC50 of 17 nM. AZ506 inhibits SMYD2 methyltransferase activity in cells, leading to a decrease in the SMYD2-mediated methylation signal[1].
Web ID
– HY-134828
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C33H40N6O
References
– [1]Cowen SD, et al. Design, Synthesis, and Biological Activity of Substrate Competitive SMYD2 Inhibitors. J Med Chem. 2016;59(24):11079-11097.
CAS Number
– 2043321-54-4
Molecular Weight
– 536.71
Compound Purity
– 99.74
SMILES
– O=C(C1=CC(C2=CC=CC=C2N3CCN(CCC4=CNC5=C4C=CC=C5)CC3)=CN=C1)NCCCN6CCCC6
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 50 mg/mL (ultrasonic)
Target
– Histone Methyltransferase
Isoform
– SMYD2
Pathway
– Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
