Avanbulin

SKU T21317-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 69 CAD through 120 CAD

Products Details

Product Description

– Avanbulin is a potent inhibitor of tubulin polymerization with antitumor activity. It elicits a unique microtubule (MT) phenotype, distinct from colchicine, paclitaxel, and vinblastine has broad in vitro anti-proliferative activity against a diverse range of human tumor lines at low nM IC50s.

Web ID

– T21317

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C20H17N7O2

References

– Prota AE, Danel F, Bachmann F, Bargsten K, Buey RM, Pohlmann J, Reinelt S, Lane H, Steinmetz MO. The novel microtubule-destabilizing drug BAL27862 binds to  the colchicine site of tubulin with distinct effects on microtubule organization. J Mol Biol. 2014 Apr 17;426(8):1848-60. doi: 10.1016/j.jmb.2014.02.005. Epub 2014 Feb 11. PubMed PMID: 24530796.

CAS Number

– 798577-91-0

Molecular Weight

– C20H17N7O2

SMILES

– Nc1ccc(cc1)C(=O)Cn1c(nc2ccccc12)-c1nonc1NCCC#N

Target

– Calcium Channel

Pathway

– Others

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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