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Products Details
Product Description
– Aurora-A ligand 1 is a potent and selective inhibitor of Aurora-A, exhibiting a dissociation constant (Kd) of 0.85 nM. It serves as a target protein ligand [PROTAC target protein ligand] in the development of PROTAC Aurora-A degraders with antitumor activity. Additionally, Aurora-A ligand 1 is utilized in the synthesis of HLB-0532259, which exhibits antitumor effects against neuroblastoma.
Web ID
– T204142
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C21H23N5O3
CAS Number
– 2541626-73-5
Molecular Weight
– C21H23N5O3
SMILES
– O=C(O)C1=CC=C(C=C1)NC=2N=CC=3C=C(C(=O)N(C)C)N(C3N2)C4CCCC4
Target
– Others
Pathway
– Chromatin/Epigenetic|||Cell Cycle/Checkpoint|||PROTAC
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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