Download Files:
Products Details
Product Description
– ATX inhibitor 20 (compound 24) is a potent ATX (autotaxin) inhibitor, with an IC50 of 2.3 nM[1].
Web ID
– HY-146123
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C31H34FN5O3
References
– [1]Jia F, et al. Structure-based linker exploration: Discovery of 1-ethyl-1H-indole analogs as novel ATX inhibitors. Bioorg Med Chem. 2020 Nov 15;28(22):115795.
CAS Number
– 2691937-03-6
Molecular Weight
– 543.63
SMILES
– O=C(NC1=CC2=C(N(CC)C=C2NC(NCC3=CC=C(F)C=C3)=O)C=C1)C4=CC=C(CN5CCC(O)CC5)C=C4
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Phosphodiesterase (PDE)
Isoform
– Autotaxin
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
