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Products Details
Product Description
– ATRA-hydroxyimino (CRABP-II ligand 1), the Retinoic acid (ATRA)-based moiety, binds to cIAP1 ligand (Bestatin) via a linker to form SNIPER to degrade CRABP-II in IMR-32 cells[1].
Web ID
– HY-111839
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C20H27NO3
References
– [1]Scheepstra M, et al. Bivalent Ligands for Protein Degradation in Drug Discovery. Comput Struct Biotechnol J. 2019 Jan 25;17:160-176.
CAS Number
– 135325-47-2
Molecular Weight
– 329.43
SMILES
– CC1=C(/C=C/C(C)=C/C=C/C(C)=C/C(O)=O)C(C)(C)CC/C1=NO
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Ligands for Target Protein for PROTAC
Pathway
– PROTAC
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
