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Products Details
Product Description
– ATM-IN-1 is a potent inhibitor of ATM. ATM is located mainly in the nucleus and microsomes and is involved in cell cycle progression and in the cell cycle checkpoint response to DNA damage. ATM-IN-1 has the potential for the research of cancer and neurology diseases (extracted from patent WO2021139814A1, compound 3)[1].
Web ID
– HY-142931
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C30H36N6O3
References
– [1]Wenyuan Qian, et al. Quinoline and imidazole compounds and their applications. Patent WO2021139814A1.
CAS Number
– 2662761-76-2
Molecular Weight
– 528.65
SMILES
– O=C(N1N2CCOCC2)N(C3CC3)C4=C1C5=CC(C6=CC=C(OCCCN7CCCCC7)N=C6)=CC=C5N=C4
Clinical Information
– No Development Reported
Research Area
– Cancer; Neurological Disease
Solubility
– 10 mM in DMSO
Target
– ATM/ATR
Pathway
– Cell Cycle/DNA Damage;PI3K/Akt/mTOR
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
