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AS604872
SKU
HY-118388-Get quote
Category Reference compound
Tags Endocrinology, GPCR/G Protein, Prostaglandin Receptor
Products Details
Product Description
– AS604872 is an orally active, potent and selective prostaglandin F2α receptor (FP) antagonist with a Ki of 35 nM in humans, 158 nM in rats and 323 nM in mice. AS604872 inhibits contractions and delays labour[1].
Web ID
– HY-118388
Shipping
– Room temperature
Molecular Formula
– C28H25N3O3S2
References
– [1]Rocco Cirillo, et al. Arrest of preterm labor in rat and mouse by an oral and selective nonprostanoid antagonist of the prostaglandin F2alpha receptor (FP). Am J Obstet Gynecol. 2007 Jul;197(1):54.e1-9.
CAS Number
– 612532-48-6
Molecular Weight
– 515.65
SMILES
– O=C([C@H]1N(CCS1)S(=O)(C2=CC=C(C3=CC=CC=C3)C=C2)=O)N[C@@H](C4=CC=CC=N4)C5=CC=CC=C5
Clinical Information
– No Development Reported
Research Area
– Endocrinology
Solubility
– 10 mM in DMSO
Target
– Prostaglandin Receptor
Pathway
– GPCR/G Protein
Product type
– Reference compound
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