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ART558
Price range: 248 CAD through 3,664 CAD
Products Details
Product Description
– ART558 is a potent, selective, low molecular weight, allosteric DNA polymerase activity of Polθ inhibitor (IC50=7.9 nM). ART558 can be used for the research of cancer.
Web ID
– T9275
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C21H21F3N4O2
References
– Zatreanu D, et al. Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance. Nat Commun. 2021 Jun 17;12(1):3636.
CAS Number
– 2603528-97-6
Molecular Weight
– C21H21F3N4O2
Compound Purity
– 0.9967
SMILES
– CN(C(=O)[C@@H]1[C@H](O)CCN1c1nc(C)cc(c1C#N)C(F)(F)F)c1cccc(C)c1
Pathway
– Cell Cycle/Checkpoint|||DNA Damage/DNA Repair
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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