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ARD-266
Price range: 1,019 CAD through 7,968 CAD
Products Details
Product Description
– ARD-266 is a PROTAC degrader based on the von Hippel-Lindau E3 ligase, inducing the degradation of AR proteins, and can be used in prostate cancer research.
Web ID
– T13552
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C52H59ClN6O7
References
– Han X, et al. Discovery of Highly Potent and Efficient PROTAC Degraders of Androgen Receptor (AR) by Employing Weak Binding Affinity VHL E3 Ligase Ligands. J Med Chem. 2019 Dec 26;62(24):11218-11231.
CAS Number
– 2666951-70-6
Molecular Weight
– C52H59ClN6O7
Compound Purity
– 0.9989
SMILES
– O([C@@H]1C(C)(C)[C@@H](NC(=O)C2=CC=C(C#CC3CCN(C(C[C@H](NC(=O)[C@H]4N(C([C@H]([C@H](C)C)C=5ON=C(C)C5)=O)C[C@H](O)C4)C6=CC=CC=C6)=O)CC3)C=C2)C1(C)C)C7=CC(Cl)=C(C#N)C=C7
Target
– NF-κB|||Liver X Receptor|||Antibacterial
Pathway
– Endocrinology/Hormones|||PROTAC
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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