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AR antagonist 1
Price range: 125 CAD through 1,325 CAD
Products Details
Product Description
– AR antagonist 1 is a potent antagonist of the androgen receptor. It binds to E3 ligase ligands with weak binding affinities to VHL protein in the synthesis of PROTAC ARD-266.
Web ID
– T10359
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C15H19ClN2O
References
– Han X, et al. Discovery of Highly Potent and Efficient PROTAC Degraders of Androgen Receptor (AR) by Employing Weak Binding Affinity VHL E3 Ligase Ligands. J Med Chem. 2019 Dec 26;62(24):11218-11231.
CAS Number
– 1818885-54-9
Molecular Weight
– C15H19ClN2O
Compound Purity
– 0.9907
SMILES
– CC1(C)[C@H](N)C(C)(C)[C@H]1Oc1ccc(C#N)c(Cl)c1
Target
– Endogenous Metabolite
Pathway
– Endocrinology/Hormones|||PROTAC
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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