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Products Details
Product Description
– Apremilast D5 (CC-10004 D5) is a deuterium-labeled Apremilast. Apremilast is an orally available inhibitor of PDE-4 (IC50: 74 nM). Apremilast inhibits TNF-α release by lipopolysaccharide (IC50: 104 nM).
Web ID
– T10350
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C22H24N2O7S
References
– Perez-Aso M, et al. Apremilast, a novel phosphodiesterase 4 (PDE4) inhibitor, regulates inflammation through multiple cAMP downstream effectors. Arthritis Res Ther. 2015 Sep 15;17:249.
CAS Number
– 1258597-47-5
Molecular Weight
– C22H24N2O7S
SMILES
– [2H]C([2H])([2H])C([2H])([2H])Oc1cc(ccc1OC)[C@@H](CS(C)(=O)=O)N1C(=O)c2cccc(NC(C)=O)c2C1=O
Target
– Others
Product type
– Isotope products
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