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Products Details
Product Description
– APN- NH2 is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. APN- NH2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Web ID
– HY-140348
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C13H13N3O
References
– [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
CAS Number
– 1539292-61-9
Molecular Weight
– 227.26
SMILES
– O=C(NC1=CC=C(C#CC#N)C=C1)CCCN
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– PROTAC Linkers
Isoform
– Alkyl-Chain Linkers
Pathway
– PROTAC
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
