Download Files:
Products Details
Product Description
– Antimalarial agent 8 (Compound 7e) is a novel orally active class of antimalarials. Antimalarial agent 8 is potent in vitro against P. falciparum and is orally efficacious (40 mg/kg) in an in vivo mouse model of malaria[1].
Web ID
– HY-145704
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C22H21Cl3N4O
References
– [1]Mathew J, et al. Malaria Box-Inspired Discovery of N-Aminoalkyl-β-carboline-3-carboxamides, a Novel Orally Active Class of Antimalarials. ACS Med Chem Lett. 2022;13(3):365-370.
CAS Number
– 2715222-97-0
Molecular Weight
– 463.79
SMILES
– O=C(C1=CC2=C(NC3=C2C=CC=C3C)C(C4=CC(Cl)=C(Cl)C=C4)=N1)NCCNC.Cl
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Parasite
Isoform
– Plasmodium
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
