Products Details

Product Description

– Antimalarial agent 15 (Compound 4e) is a parasite inhibitor. Antimalarial agent 15 shows antimalarial activity, and can inhibit P. falciparum 3D7 parasite growth (IC50=20 nM)[1].

Web ID

– HY-150065

Shipping

– Room temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C29H30N2O6

References

– [1]Nobuo Cho, et al. New antimalarials identified by a cell-based phenotypic approach: Structure-activity relationships of 2,3,4,9-tetrahydro-1H-β-carboline derivatives possessing a 2-((coumarin-5-yl)oxy)alkanoyl moiety. Bioorg Med Chem. 2022 Jul 15;66:116830.

CAS Number

– 956928-33-9

Molecular Weight

– 502.56

SMILES

– CCCCC1=CC(OC2=C1C(OCC(N3CC4=C(C5=C(N4)C=CC=C5)C[C@H]3C(OC)=O)=O)=CC(C)=C2)=O

Clinical Information

– No Development Reported

Research Area

– Infection; Inflammation/Immunology

Solubility

– 10 mM in DMSO

Target

– Parasite

Isoform

– Plasmodium

Pathway

– Anti-infection

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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