Download Files:
Products Details
Product Description
– Aniline-MPB-amino-C3-PBD is a cytotoxic agent comprised non-alkylating group. Aniline-MPB-amino-C3-PBD is a sequence-selective DNA minor-groove binding agent. Aniline-MPB-amino-C3-PBD acts as the payload for ADCs. Antimicrobial activity[1].
Web ID
– HY-135900
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C42H46N8O6
References
– [1]David Edwin Thurston, et al. Polycyclic amides as cytotoxic agents. WO2020049286A1.
CAS Number
– 2412923-79-4
Molecular Weight
– 758.86
SMILES
– O=C(N(CCCC1)[C@]1([H])CN2)C3=C2C=C(OCCCC(NC4=CN(C)C(C(NC5=CC=C(C6=CN(C)C(C(NC7=CC=C(N)C=C7)=O)=C6)C=C5)=O)=C4)=O)C(OC)=C3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– ADC Cytotoxin;Bacterial
Isoform
– Pyrrolobenzodiazepines
Pathway
– Antibody-drug Conjugate/ADC Related;Anti-infection
Product type
– ADC Related
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
