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Products Details
Product Description
– Androgen receptor antagonist 7 is an effective androgen receptor (AR) antagonist with an IC50 value of 1.18 µM. Androgen receptor antagonist 7 has biological activity in vitro and inhibits the expression of AR target in a time and dose dependent manner with an GI50 value of 7.9 µM [1].
Web ID
– HY-152524
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C27H35FN2O
References
– [1]Peřina M, et al. A-ring-fused pyrazoles of dihydrotestosterone targeting prostate cancer cells via the downregulation of the androgen receptor. Eur J Med Chem. 2023 Jan 13;249:115086.
CAS Number
– 2409791-89-3
Molecular Weight
– 422.58
SMILES
– [H][C@@]12CC[C@]3([C@@]4(CC[C@@H]([C@]4(CC[C@@]3([C@]1(CC5=C(N(N=C5C2)C6=CC=C(C=C6)F)C)C)[H])C)O)[H])[H]
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Androgen Receptor
Pathway
– Vitamin D Related/Nuclear Receptor
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
