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Products Details
Product Description
– Ancistrotecine B (Compound 2) is a Nav1.7 channel inhibitor (IC50: 0.73 μM). Ancistrotecine B relieves inflammatory pain in mice[1].
Web ID
– HY-155236
Shipping
– Room temperature
Molecular Formula
– C26H31NO4
References
– [1]Wang QQ, et al. Naphthylisoquinoline alkaloids, a new structural template inhibitor of Nav1.7 sodium channel. Acta Pharmacol Sin. 2023 Sep;44(9):1768-1776.
Molecular Weight
– 421.53
SMILES
– C[C@@H]1N(C)[C@@H](C)C2=C(OC)C(C3=CC=C(O)C4=C3C=C(C)C=C4OC)=C(OC)C=C2C1
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Sodium Channel
Pathway
– Membrane Transporter/Ion Channel
Product type
– Natural Products
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
