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Products Details
Product Description
– AmPEG6C2-Aur0131 is a agent-linker conjugate for ADC (anti-CXCR4 ADC) with potent antitumor activity by using Aur0131 (an auristatin microtubule inhibitor), linked via the non-cleavable linker AmPEG6C2[1].
Web ID
– HY-111555
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C54H92N6O15
References
– [1]Costa MJ, et al. Optimal design, anti-tumour efficacy and tolerability of anti-CXCR4 antibody drug conjugates. Sci Rep. 2019 Feb 21;9(1):2443.
CAS Number
– 1650569-94-0
Molecular Weight
– 1065.34
SMILES
– NCCOCCOCCOCCOCCOCCOCCC(N1[C@@](C(N[C@@H](C(C)C)C(N(C)[C@@H]([C@@H](C)CC)[C@H](OC)CC(N2[C@H]([C@H](OC)[C@@H](C)C(N[C@@H](CC3=CC=CC=C3)C(O)=O)=O)CCC2)=O)=O)=O)(C)CCC1)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Drug-Linker Conjugates for ADC;Microtubule/Tubulin
Isoform
– Traditional Cytotoxic Agents
Pathway
– Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage;Cytoskeleton
Product type
– ADC Related
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
