Amlexanox

SKU T1639-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 51 CAD through 373 CAD

Products Details

Product Description

– Amlexanox (AA673) is an anti-aphthous ulcer drug. Amlexanox inhibits the synthesis and release of inflammatory mediators, including leukotrienes and histamine, from mast cells, neutrophils, and mononuclear cells. Amlexanox also acts as a leukotriene D4 antagonist and a phosphodiesterase inhibitor. Amlexanox decreases the time ulcers take to heal as well as the pain associated with the ulcers.

Web ID

– T1639

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C16H14N2O4

Citations

– 1. Cheng C, Ji Z, Sheng Y, et al. Aphthous ulcer drug inhibits prostate tumor metastasis by targeting IKKɛ/TBK1/NF-κB signaling. Theranostics. 2018, 8(17): 4633

References

– Reilly SM, et al. An inhibitor of the protein kinases TBK1 and IKK-e improves obesity-related metabolic dysfunctions in mice. Nat Med. 2013 Mar;19(3):313-21.

CAS Number

– 68302-57-8

Molecular Weight

– C16H14N2O4

Compound Purity

– 0.9967

SMILES

– CC(C)C1=CC=C2OC3=NC(N)=C(C=C3C(=O)C2=C1)C(O)=O

Target

– Parasite

Pathway

– NF-κB|||Angiogenesis|||Immunology/Inflammation|||Tyrosine Kinase/Adaptors

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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