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AF38469
$110 – $1,650
Products Details
Product Description
– AF38469 is a selective, orally bioavailable Sortilin inhibitor with an IC50 value of 330 nM.
Web ID
– HY-12802
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Molecular Formula
– C15H11F3N2O3
References
– [1]Schroder TJ, et al. The identification of AF38469: an orally bioavailable inhibitor of the VPS10P family sorting receptor Sortilin. Bioorg Med Chem Lett. 2014 Jan 1;24(1):177-80.
CAS Number
– 1531634-31-7
Molecular Weight
– 324.25
Compound Purity
– 99.28
SMILES
– O=C(NC1=CC=CC(C)=N1)C2=CC=C(C(F)(F)F)C=C2C(O)=O
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– DMSO : ≥ 43 mg/mL
Target
– Neurotensin Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
