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ADU-S100
1,326 CAD
Only 1000 item(s) left in stock.
Products Details
Product Description
– ADU-S100 (MIW815) is a cyclic dinucleotide (CDN) class STING agonist that significantly induces the production of IFN-β and pro-inflammatory cytokines TNF-α, IL-6, and MCP-1, induces TBK1 and IRF3 phosphorylation, and exhibits antitumour activity.
Web ID
– T10252L3
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C20H24N10O10P2S2
References
– Corrales L, et al. Direct Activation of STING in the Tumor Microenvironment Leads to Potent and Systemic Tumor Regression and Immunity. Cell Rep. 2015 May 19;11(7):1018-30.
CAS Number
– 1638241-89-0
Molecular Weight
– C20H24N10O10P2S2
Compound Purity
– 0.9983
SMILES
– O[C@H]1[C@]2([H])[C@H](N3C4=NC=NC(N)=C4N=C3)OC1([H])CO[P@@](O[C@]5([H])[C@@](O[C@@H](N6C7=NC=NC(N)=C7N=C6)[C@@H]5O)([H])CO[P@](O2)(S)=O)(S)=O
Target
– Others
Pathway
– Neuroscience|||Apoptosis|||NF-κB|||Immunology/Inflammation|||Others
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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