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Adenosine 5′-diphosphoribose (sodium)
$77 – $120
Products Details
Product Description
– Adenosine 5′-diphosphoribose sodium (ADP ribose sodium) is a nicotinamide adenine nucleotide (NAD+) metabolite. Adenosine 5′-diphosphoribose sodium is the most potent and primary intracellular Ca2+-permeable cation TRPM2 channel activator. Adenosine 5′-diphosphoribose sodium also can enhance autophagy[1][2].
Web ID
– HY-100973A
Storage Temperature
– -20°C (Powder, sealed storage, away from moisture)
Shipping
– Blue Ice
Applications
– Cancer-programmed cell death
Molecular Formula
– C15H22N5NaO14P2
References
– [1]Zhang DX, et al. The potential regulatory roles of NAD(+) and its metabolism in autophagy. Metabolism. 2016 Apr;65(4):454-62.|[2] Tóth B, et al. Pore collapse underlies irreversible inactivation of TRPM2 cation channel currents. Proc Natl Acad Sci U S A. 2012 Aug 14;109(33):13440-5.
CAS Number
– 68414-18-6
Molecular Weight
– 581.30
Compound Purity
– 99.03
SMILES
– O[C@H]([C@@H]1O)[C@@H](O[C@@H]1COP(OP(OC[C@@H](O)[C@@H](O)[C@@H](O)C=O)([O-])=O)(O)=O)N2C(N=CN=C3N)=C3N=C2.[Na+]
Clinical Information
– Phase 1
Research Area
– Endocrinology; Metabolic Disease; Cancer
Solubility
– DMSO : 25 mg/mL (ultrasonic;warming;heat to 80°C)|H2O : 125 mg/mL (ultrasonic)
Target
– Autophagy;TRP Channel
Pathway
– Autophagy;Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
