Download Files:
AD 01
405 CAD
Only 1000 item(s) left in stock.
Products Details
Product Description
– FKBPL (FK506-binding protein like)-based peptide. Binds to and upregulates expression of CD44. Inhibits breast cancer stem cell (BCSC) growth. Decreases pluripotency markers and promotes differentiation of BCSCs. Also inhibits endothelial cell migration as well as tubule and microvessel formation in vitro and in vivo. Blocks tumor growth in xenograft models.
Web ID
– TP2079
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C115H187N33O42
References
– Yakkundi et al (2013) The anti-migratory effects of FKBPL and its peptide derivative, AD-01: regulation of CD44 and the cytoskeletal pathway. PLoS One. 8 e55075 PMID:
CAS Number
– 959961-23-0
Molecular Weight
– C115H187N33O42
SMILES
– C(=O)([C@H]1N(C([C@@H](NC([C@@H](NC(=O)[C@H]2N(C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCC(N)=O)N)=O)[C@H](CC)C)=O)CCCNC(=N)N)=O)CCC(N)=O)=O)CCC(N)=O)=O)CCC2)CCCNC(=N)N)=O)CC(O)=O)=O)CCC1)N3[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N4[C@H](C(N[C@H](C(=O)N5[C@H](C(N[C@H](C(N[C@H](C(O)=O)CO)=O)C)=O)CCC5)CC(O)=O)=O)CCC4)CO)=O)[C@H](C)C)=O)CCC(O)=O)=O)CC(C)C)=O)CCC(O)=O)=O)CC(C)C)=O)[C@@H](C)O)=O)CCC(O)=O)=O)[C@@H](C)O)=O)CCC3
Product type
– Peptide
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
Related Products
1000 in stock
1000 in stock
