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Acridine Orange (hydrochloride)
$60 – $66
Products Details
Product Description
– Acridine Orange hydrochloride is a cell-penetrable nucleic acid-selective fluorescent dye. Acridine Orange hydrochloride produces orange fluorescence when it binds to ssDNA or RNA, and green fluorescence when it binds to dsDNA (Ex: 488 nM; Em: green fluorescence at 530 nm, orange fluorescence at 640 nm)[1][2][3].
Web ID
– HY-101879
Storage Temperature
– 4°C (Powder, protect from light, stored under nitrogen)
Shipping
– Room Temperature
Molecular Formula
– C17H20ClN3
Citations
– Acta Pharm Sin B. 2021 Feb 11.|Adv Funct Mater. 2023 Apr 14.|Cell Death Dis. 2020 Jul 30;11(7):607.|Cell Death Dis. 2021 Jan 13;12(1):80.|Cell Prolif. 2021 Dec 24;e13172.|Clin Transl Med. 2023 Mar;13(3):e1229.|Environ Toxicol. 2023 May 20.|Free Radic Biol Med. 2023 Sep 1;208:402-417.|Int J Mol Med. 2023 Apr 7.|Int J Mol Sci. 2023 Sep 5, 24(18), 13812.|Microbiol Spectr. 2023 May 1;e0313822.|Nat Commun. 2023 Jun 30;14(1):3877.|SSRN. 2023 Mar 9.|SSRN. 2023 Nov 15.|Chemosphere. 2023 Apr;320:138071.|Research Square Print. December 12th, 2022.
References
– [1]McMaster GK, et al. Analysis of single- and double-stranded nucleic acids on polyacrylamide and agarosegels by using glyoxal and acridine orange. Proc Natl Acad Sci U S A. 1977 Nov;74(11):4835-8.|[2]Traganos F, et al. Simultaneous staining of ribonucleic and deoxyribonucleic acids in unfixed cells using acridine orange in a flow cytofluorometric system. J Histochem Cytochem. 1977 Jan;25(1):46-56.|[3]Byvaltsev VA, et al. Acridine Orange: A Review of Novel Applications for Surgical Cancer Imaging and Therapy. Front Oncol. 2019 Sep 24;9:925. |[4]Wang Q, et al. Substrate stiffness regulates the differentiation profile and functions of osteoclasts via cytoskeletal arrangement. Cell Prolif. 2022 Jan;55(1):e13172.
CAS Number
– 65-61-2
Molecular Weight
– 301.81
Compound Purity
– 99.86
SMILES
– CN(C)C1=CC=C2C(N=C3C=C(N(C)C)C=CC3=C2)=C1.[H]Cl
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– DMSO : 25 mg/mL (ultrasonic)|H2O : 50 mg/mL (ultrasonic;heat to 60°C)
Target
– DNA Stain;Fluorescent Dye;Parasite
Pathway
– Anti-infection;Cell Cycle/DNA Damage;Others
Product type
– Dye Reagents
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
