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Products Details
Product Description
– AChE-IN-30 is an AChE inhibitor with an IC50 value of 4.4 μM. AChE-IN-30 has neuroprotective activity, and inhibits H2O2-induced apoptosis by suppressing intracellular ROS accumulation. AChE-IN-30 can be used for research of Alzheimer’s disease[1].
Web ID
– HY-155022
Shipping
– Room temperature
Molecular Formula
– C22H24N4O2
References
– [1]Wan D, et al. Design, Synthesis, and Biological Activity of Donepezil: Aromatic Amine Hybrids as Anti-Alzheimerss Drugs. ACS Omega. 2023 Jun 5;8(24):21802-21812.
CAS Number
– 2937454-22-1
Molecular Weight
– 376.45
SMILES
– NC1=CC=C(NC2=C(NC3CCN(CC4=CC=CC=C4)CC3)C(C2=O)=O)C=C1
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Cholinesterase (ChE)
Pathway
– Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
