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Products Details
Product Description
– AChE/hCA I/II-IN-1 (Compound 6) is a potent inhibitor of AChE/Hca with IC50 values of 22.21, 60.79 and 66.64 nM for AChE, Hca â… and Hca â…¡. AChE/hCA I/II-IN-1 can be used for the rsearch for glaucoma, Alzheimer’s disease, diabetes[1].
Web ID
– HY-149012
Shipping
– Room temperature
Applications
– Metabolism-sugar/lipid metabolism
Molecular Formula
– C15H13N3S
References
– [1]Gülçin Ä°, et al. Synthesis of nitrogen, phosphorus, selenium and sulfur-containing heterocyclic compounds – Determination of their carbonic anhydrase, acetylcholinesterase, butyrylcholinesterase and α-glycosidase inhibition properties. Bioorg Chem. 2020 Oct;103:104171.
CAS Number
– 2049681-10-7
Molecular Weight
– 267.35
SMILES
– NC1=NC(C2=CC=CS2)=CC(CC3=CC=CC=C3)=N1
Clinical Information
– No Development Reported
Research Area
– Endocrinology; Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Carbonic Anhydrase;Cholinesterase (ChE)
Isoform
– AChE;CA â…¡
Pathway
– Metabolic Enzyme/Protease;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
