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AChE/BChE-IN-13
SKU
HY-155708-Get quote
Category Reference compound
Tags Cholinesterase (ChE), Neurological Disease, Neuronal Signaling
Products Details
Product Description
– AChE/BChE-IN-13 (compound 5j) is a potent dual inhibitor of AChE and BChE with IC50s of 20.89 and 17.37 μM, respectively. AChE/BChE-IN-13 can be used in Alzheimer’s disease (AD) research[1].
Web ID
– HY-155708
Shipping
– Room temperature
Molecular Formula
– C21H18N8O7
References
– [1]Pourtaher H, et al. The anti-Alzheimer potential of novel spiroindolin-1,2-diazepine derivatives as targeted cholinesterase inhibitors with modified substituents. Sci Rep. 2023 Jul 24;13(1):11952.
Molecular Weight
– 494.42
SMILES
– NC1=C(C#N)C2(C3=C(NC2=O)C=CC([N+]([O-])=O)=C3)C([N+]([O-])=O)=C(NC4=CC(OC)=CC=C4OC)NN1
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Cholinesterase (ChE)
Pathway
– Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.