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Products Details
Product Description
– Acetaminophen (APAP) is a COX inhibitor that inhibits COX-1 and COX-2 (IC50=113.7/25.8 μM). Acetaminophen has antipyretic and analgesic activity as well as weak anti-inflammatory activity.
Web ID
– T0065
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C8H9NO2
Citations
– 1. Ma R, Fang L, Chen L, et al. Ferroptotic stress promotes macrophages against intracellular bacteria. Theranostics. 2022, 12(5): 2266
2. Guo J, Xu Y, Chen L J, et al. Gut Microbiota and Host Cyp450s Co-contribute to Pharmacokinetic Variability in Mice With Non-Alcoholic Steatohepatitis: Vary From Drug to Drug. Journal of Advanced Research. 2021
References
– Vad NM, et al. Biochemical mechanism of acetaminophen (APAP) induced toxicity in melanoma cell lines. J Pharm Sci. 2009 Apr;98(4):1409-25.
CAS Number
– 103-90-2
Molecular Weight
– C8H9NO2
Compound Purity
– 0.9996
SMILES
– CC(=O)NC1=CC=C(O)C=C1
Target
– Adenosine Receptor|||ROS|||Endogenous Metabolite
Pathway
– Chromatin/Epigenetic|||Immunology/Inflammation|||Metabolism|||Neuroscience
Product type
– Natural Product
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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