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Ac-YVAD-CMK
Price range: 102 CAD through 1,390 CAD
Products Details
Product Description
– Ac-YVAD-CMK (Ac-Tyr-Val-Ala-Asp-CMK) is a selective and irreversible inhibitor of Caspase-1 and inhibits pyroptosis, IL-1β and IL-18. Ac-YVAD-CMK shows neuroprotective and anti-inflammatory capacity.
Web ID
– T36347
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C24H33ClN4O8
References
– Rabuffetti, M., Sciorati, C., Tarozzo, G., et al. Inhibition of caspase-1-like activity by Ac-Tyr-Val-Ala-Asp-chloromethyl ketone induces long-lasting neuroprotection in cerebral ischemia through apoptosis reduction and decrease of proinflammatory cytokines. Journal of Neuroscience 20, 4398-4404 (2000).
CAS Number
– 178603-78-6
Molecular Weight
– C24H33ClN4O8
Compound Purity
– 0.9949
SMILES
– CC(C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(C)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)CCl
Target
– c-Met/HGFR
Pathway
– Apoptosis|||Proteases/Proteasome|||Immunology/Inflammation
Product type
– Peptide
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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