Ac-VLPE-FMK

SKU HY-153614-1 mg Category Tags , ,

$380$1,200

Products Details

Product Description

– Ac-VLPE-FMK, a tetrapeptidyl mono-fluoromethyl ketone (m-FMK), is a Cat-B and Cat-L inhibitor. Ac-VLPE-FMK can be used for the research of cancer aggressiveness[1][2].

Web ID

– HY-153614

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Molecular Formula

– C25H41FN4O7

References

– [1]RudziÅ„ska M, et, al. Cysteine Cathepsins Inhibition Affects Their Expression and Human Renal Cancer Cell Phenotype. Cancers (Basel). 2020 May 21;12(5):1310.|[2]Citarella A, et, al. Peptidyl Fluoromethyl Ketones and Their Applications in Medicinal Chemistry. Molecules. 2020 Sep 3;25(17):4031.

CAS Number

– 2679825-27-3

Molecular Weight

– 528.61

Compound Purity

– 99.0

SMILES

– O=C(N(CCC1)[C@@H]1C(N[C@H](C(CF)=O)CCC(OC)=O)=O)[C@H](CC(C)C)NC([C@H](C(C)C)NC(C)=O)=O

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– Cathepsin

Isoform

– Cathepsin B;Cathepsin L

Pathway

– Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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