Products Details

Product Description

– Ac-VDVAD-CHO is a caspase-2/3 inhibitor (IC50: 46 and 15 nM)[1].

Web ID

– HY-134567

Shipping

– Room temperature

Molecular Formula

– C23H37N5O10

References

– [1]Maillard MC, et al. Exploiting differences in caspase-2 and -3 Sâ‚‚ subsites for selectivity: structure-based design, solid-phase synthesis and in vitro activity of novel substrate-based caspase-2 inhibitors. Bioorg Med Chem. 2011 Oct 1;19(19):5833-51.

CAS Number

– 194022-51-0

Molecular Weight

– 543.57

SMILES

– CC(N[C@@H](C(C)C)C(N[C@@H](CC(O)=O)C(N[C@@H](C(C)C)C(N[C@@H](C)C(N[C@H](C=O)CC(O)=O)=O)=O)=O)=O)=O

Clinical Information

– No Development Reported

Research Area

– Others

Solubility

– 10 mM in DMSO

Target

– Casein Kinase

Pathway

– Cell Cycle/DNA Damage;Stem Cell/Wnt

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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