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Ac-DNLD-CHO
SKU
HY-136733-Get quote
Category Reference compound
Tags Apoptosis, Caspase, Infection; Neurological Disease
Products Details
Product Description
– Ac-DNLD-CHO (Ac-Asp-Asn-Leu-Asp-CHO) is a Caspase-3/7 inhibitor (IC50: 9.89, 245 nM respectively; Kiapp: 0.68, 55.7 nM respectively). Ac-DNLD-CHO can be used for research of caspase-mediated apoptosis diseases, such as neurodegenerative disorders and viral infection diseases[1].
Web ID
– HY-136733
Shipping
– Room temperature
Molecular Formula
– C20H31N5O10
References
– [1]Yoshimori A, et al. Structural and functional definition of the specificity of a novel caspase-3 inhibitor, Ac-DNLD-CHO. BMC Pharmacol. 2007 Jun 27;7:8.
CAS Number
– 775289-20-8
Molecular Weight
– 501.49
SMILES
– O=C(N[C@@H](CC(C)C)C(N[C@H](C=O)CC(O)=O)=O)[C@H](CC(N)=O)NC([C@@H](NC(C)=O)CC(O)=O)=O
Clinical Information
– No Development Reported
Research Area
– Infection; Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Caspase
Pathway
– Apoptosis
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.