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Products Details
Product Description
– Abacavir-d4 is the deuterium labeled Abacavir. Abacavir is a potent nucleoside analog reverse-transcriptase inhibitor (NRTI)[1][2].
Web ID
– HY-17423S
Shipping
– Room temperature
Molecular Formula
– C14H14D4N6O
References
– [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Charneira C, et al. Reactive aldehyde metabolites from the anti-HIV drug abacavir: amino acid adducts as possible factors in abacavir toxicity. Chem Res Toxicol. 2011 Dec 19;24(12):2129-41.|[3]Hervey PS, et al. Abacavir: a review of its clinical potential in patients with HIV infection. Drugs. 2000 Aug;60(2):447-79.
CAS Number
– 1260619-56-4
Molecular Weight
– 290.36
SMILES
– OC[C@@H]1C=C[C@H](N2C=NC3=C(NC4C([2H])([2H])C4([2H])[2H])N=C(N)N=C23)C1
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Apoptosis;HIV;Isotope-Labeled Compounds;Reverse Transcriptase
Pathway
– Anti-infection;Apoptosis;Others
Product type
– Isotope-Labeled Compounds
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
