Download Files:
A2A receptor antagonist 1
$80 – $1,350
Products Details
Product Description
– A2A receptor antagonist 1 (CPI-444 analog) is an antagonist of both adenosine A2A receptor and A1 receptor with Ki values of 4 and 264 nM, respectively[1].
Web ID
– HY-102024
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C16H12FN5O
References
– [1]Gillespie RJ, et al. Antagonists of the human adenosine A2A receptor. Part 3: Design and synthesis of pyrazolo[3,4-d]pyrimidines, pyrrolo[2,3-d]pyrimidines and 6-arylpurines. Bioorg Med Chem Lett. 2008 May 1;18(9):2924-9.
CAS Number
– 443103-97-7
Molecular Weight
– 309.30
Compound Purity
– 99.96
SMILES
– NC1=NC(C2=CC=CO2)=C3C(N(CC4=C(F)C=CC=C4)N=C3)=N1
Clinical Information
– No Development Reported
Research Area
– Cancer; Neurological Disease
Solubility
– DMSO : 25 mg/mL (ultrasonic)
Target
– Adenosine Receptor
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
