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A1874
Price range: 134 CAD through 3,888 CAD
Products Details
Product Description
– A1874 is a nutlin-based and BRD4-degrading PROTAC which induces BRD4 degradation in cells. Effective in inhibiting many cancer cell lines proliferation.
Web ID
– T5442
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C58H62Cl3F2N9O7S
References
– Hines J, Lartigue S, Dong H.et.al.MDM2-Recruiting PROTAC Offers Superior, Synergistic Antiproliferative Activity via Simultaneous Degradation of BRD4 and Stabilization of p53[J].Cancer Res. 2019 Jan 1;79(1):251-262.
CAS Number
– 2064292-12-0
Molecular Weight
– C58H62Cl3F2N9O7S
Compound Purity
– 0.9952
SMILES
– C(#N)[C@]1([C@H]([C@H](C(NC2=C(OC)C=C(C(NCCOCCOCCOCCNC(C[C@H]3C=4N(C5=C(C(=N3)C6=CC=C(Cl)C=C6)C(C)=C(C)S5)C(C)=NN4)=O)=O)C=C2)=O)N[C@H]1CC(C)(C)C)C7=C(F)C(Cl)=CC=C7)C8=C(F)C=C(Cl)C=C8
Pathway
– Chromatin/Epigenetic|||PROTAC
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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