A031
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A031

SKU T74745-5 mg Category Brand:

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Products Details

Product Description

– A031, a potent PROTAC androgen receptor (AR) degrader, demonstrates significant efficacy with an IC50 value under 0.25 μM for AR protein degradation. Additionally, it exhibits an inhibitory impact on tumor growth in zebrafish models of human prostate cancer (VCaP) [1].

Web ID

– T74745

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C50H61ClN10O7S

CAS Number

– 2682255-44-1

Molecular Weight

– C50H61ClN10O7S

SMILES

– [H][C@]12CC[C@]([H])(C[C@@H](C1)Oc1ccc(C#N)c(Cl)c1)N2C(=O)c1cnc(nc1)N1CCN(CCOCC(=O)N[C@H](C(=O)N2C[C@H](O)C[C@H]2C(=O)N[C@@H](C)c2ccc(cc2)-c2scnc2C)C(C)(C)C)CC1

Pathway

– Others

Product type

– PROTAC

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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