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7ACC1
$102 – $162
Products Details
Product Description
– 7ACC1 (DEAC; Coumarin D 1421; D 1421) can selectively interfere with lactate flux in the tumor microenvironment and inhibit the influx of lactate in tumor cells expressing MCT1 and MCT4, but has no effect on lactate efflux.
Web ID
– HY-D0067
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C14H15NO4
References
– [1]Draoui N, et al. Antitumor activity of 7-aminocarboxycoumarin derivatives, a new class of potent inhibitors of lactate influx but not efflux. Mol Cancer Ther. 2014 Jun;13(6):1410-8.
CAS Number
– 50995-74-9
Molecular Weight
– 261.27
Compound Purity
– 99.96
SMILES
– O=C(C1=CC2=CC=C(N(CC)CC)C=C2OC1=O)O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 33.33 mg/mL (ultrasonic)
Target
– Monocarboxylate Transporter
Isoform
– MCT1
Pathway
– Membrane Transporter/Ion Channel
Product type
– Dye Reagents
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
