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Products Details
Product Description
– 7-O-(Cbz-N-amido-PEG4)-paclitaxel is a PEG-class Drug-linker conjugates for ADC, containing a paclitaxel moiety and a amino group. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. 7-O-(Cbz-N-amido-PEG4)-paclitaxel can be used in the synthesis of Antibody-Drug Conjugates (ADCs)[1].
Web ID
– HY-141148
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C66H78N2O21
References
– [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Molecular Weight
– 1235.33
SMILES
– CC1=C([C@@H](OC(C)=O)C([C@@]2(C)C([C@@](CO3)(OC(C)=O)[C@H]3C[C@@H]2OC(CCOCCOCCOCCOCCNC(OCC4=CC=CC=C4)=O)=O)[C@@H]5OC(C6=CC=CC=C6)=O)=O)C(C)(C)[C@@]5(O)C[C@@H]1OC([C@H](O)[C@@H](NC(C7=CC=CC=C7)=O)C8=CC=CC=C8)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Drug-Linker Conjugates for ADC
Isoform
– PEG Linkers
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
