7-Aminomethyl-10-methyl-11-fluoro camptothecin

$620$2,960

Products Details

Product Description

– 7-Aminomethyl-10-methyl-11-fluoro camptothecin is a cytotoxin of MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluoro camptothecin (HY-132158). 7-Aminomethyl-10-methyl-11-fluoro camptothecin can be used for the synthesis of camptothecin antibody-drug conjugate (ADC)[1].

Web ID

– HY-132160

Storage Temperature

– -20°C (Powder, sealed storage, away from moisture and light)

Shipping

– Blue Ice

Applications

– Cancer-programmed cell death

Molecular Formula

– C22H20FN3O4

References

– [1]Li W, et, al. Synthesis and Evaluation of Camptothecin Antibody-Drug Conjugates. ACS Med Chem Lett. 2019 Sep 6;10(10):1386-1392.

CAS Number

– 2378616-23-8

Molecular Weight

– 409.41

Compound Purity

– 99.30

SMILES

– NCC1=C2C(C(N3C2)=CC([C@]4(CC)O)=C(C3=O)COC4=O)=NC5=CC(F)=C(C=C51)C

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– DMSO : 60 mg/mL (ultrasonic)

Target

– ADC Cytotoxin

Pathway

– Antibody-drug Conjugate/ADC Related

Product type

– ADC Related

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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