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7-Aminomethyl-10-methyl-11-fluoro camptothecin
SKU
HY-132160-1 mg
Category ADC Related
Tags ADC Cytotoxin, Antibody-drug Conjugate/ADC Related, Cancer
$620 – $2,960
Products Details
Product Description
– 7-Aminomethyl-10-methyl-11-fluoro camptothecin is a cytotoxin of MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluoro camptothecin (HY-132158). 7-Aminomethyl-10-methyl-11-fluoro camptothecin can be used for the synthesis of camptothecin antibody-drug conjugate (ADC)[1].
Web ID
– HY-132160
Storage Temperature
– -20°C (Powder, sealed storage, away from moisture and light)
Shipping
– Blue Ice
Applications
– Cancer-programmed cell death
Molecular Formula
– C22H20FN3O4
References
– [1]Li W, et, al. Synthesis and Evaluation of Camptothecin Antibody-Drug Conjugates. ACS Med Chem Lett. 2019 Sep 6;10(10):1386-1392.
CAS Number
– 2378616-23-8
Molecular Weight
– 409.41
Compound Purity
– 99.30
SMILES
– NCC1=C2C(C(N3C2)=CC([C@]4(CC)O)=C(C3=O)COC4=O)=NC5=CC(F)=C(C=C51)C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 60 mg/mL (ultrasonic)
Target
– ADC Cytotoxin
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– ADC Related
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.