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6-Maleimidohexanoic acid N-hydroxysuccinimide ester
SKU
HY-78961-100 mg
Category ADC Related
Tags ADC Linker, Antibody-drug Conjugate/ADC Related, Cancer
$90 – $260
Products Details
Product Description
– 6-Maleimidohexanoic acid N-hydroxysuccinimide ester (EMCS) is a heterobifunctional cross-linking reagent. EMCS is used as a unique and useful reagent for preparation of hapten conjugate and enzyme immunoconjugates[1].
Web ID
– HY-78961
Storage Temperature
– -20°C (Powder, sealed storage, away from moisture and light)
Shipping
– Blue Ice
Applications
– Cancer-programmed cell death
Molecular Formula
– C14H16N2O6
References
– [1]Shinya Kida, et al. Studies on heterobifunctional cross-linking reagents, 6-maleimidohexanoic acid active esters. Chem Pharm Bull (Tokyo). 2007 Apr;55(4):685-7.|[2]Shinya Kida, et al. Evaluation of synthetic cell-penetrating peptides, Pro-rich peptide and octaargine derivatives, as adenovirus vector carrier. Protein Pept Lett. 2010 Feb;17(2):164-7.
CAS Number
– 55750-63-5
Molecular Weight
– 308.29
Compound Purity
– 99.98
SMILES
– O=C(C=C1)N(CCCCCC(ON2C(CCC2=O)=O)=O)C1=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 230 mg/mL (ultrasonic)
Target
– ADC Linker
Isoform
– Non-cleavable Linker
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– ADC Related
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.