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(5Z,2E)-CU-3

SKU T10177-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 66 CAD through 3,184 CAD

Products Details

Product Description

– (5Z,2E)-CU-3 is a potent and highly selective inhibitor of the DGKα isozyme with an IC50 value of 0.6 μM, competing with ATP and exhibiting a Km value of 0.48 mM. It specifically targets the catalytic region of DGKα without affecting the regulatory region and has demonstrated antitumor and immunogenic effects by promoting cancer cell apoptosis and T cell activation.

Web ID

– T10177

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C16H12N2O4S3

References

– Liu K, et al. A novel diacylglycerol kinase α-selective inhibitor, CU-3, induces cancer cell apoptosis and enhances immune response. J Lipid Res. 2016 Mar;57(3):368-79.

CAS Number

– 1815598-71-0

Molecular Weight

– C16H12N2O4S3

Compound Purity

– 0.9902

SMILES

– O=C1N(NS(=O)(=O)c2ccccc2)C(=S)SC1=C/C=C/c1ccco1

Target

– Others

Pathway

– Apoptosis

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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