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5,7-Dihydroxychromone
Price range: 62 CAD through 1,696 CAD
Products Details
Product Description
– 1. 5,7-Dihydroxychromone (5,7-Dihydroxy-4H-Chromen-4-One) isolated from DME is one of the active compounds that may contribute to regulate blood glucose levels. 2. 5,7-Dihydroxychromone exerts neuroprotective effect against 6-OHDA-induced oxidative stress and apoptosis by activating Nrf2/ARE signal . 3. 5,7-Dihydroxychromone induces the translocation of Nrf2 to the nucleus and increases Nrf2/ARE binding activity which results in the up-regulation of the expression of Nrf2-dependent antioxidant genes, including HO-1, NQO1, and GCLc.
Web ID
– T5S1805
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C9H6O4
References
– Kim D W , Lee K T , Kwon J , et al. Neuroprotection against 6-OHDA-induced oxidative stress and apoptosis in SH-SY5Y cells by 5,7-Dihydroxychromone: Activation of the Nrf2/ARE pathway[J]. Life Sciences, 2015, 130:25-30.
CAS Number
– 31721-94-5
Molecular Weight
– C9H6O4
Compound Purity
– 0.98
SMILES
– Oc1cc(O)c2c(c1)occc2=O
Pathway
– Apoptosis|||Microbiology/Virology|||Chromatin/Epigenetic|||DNA Damage/DNA Repair|||Proteases/Proteasome|||Immunology/Inflammation
Product type
– Natural Product
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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