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5′-O-Tritylthymidine
Price range: 2,432 CAD through 4,000 CAD
Products Details
Product Description
– 5′-O-Tritylthymidine is a blocker of the formation of the FAK/Mdm-2 complex. 5′-O-Tritylthymidine activates p53 and caspase-8. It also leads to increase detachment and apoptosis in breast and colon cancers.
Web ID
– T19906
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C29H28N2O5
References
– Golubovskaya VM, Palma NL, Zheng M, Ho B, Magis A, Ostrov D, Cance WG. A small-molecule inhibitor, 5′-O-tritylthymidine, targets FAK and Mdm-2 interaction, and blocks breast and colon tumorigenesis in vivo. Anticancer Agents Med Chem. 2013 May;13(4):532-45. PubMed PMID: 22292771; PubMed Central PMCID: PMC3625481.
CAS Number
– 7791-71-1
Molecular Weight
– C29H28N2O5
SMILES
– Cc1cn([C@H]2C[C@H](O)[C@@H](COC(c3ccccc3)(c3ccccc3)c3ccccc3)O2)c(=O)[nH]c1=O
Target
– Others
Pathway
– Others
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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