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5′-O-DMTr-2′-O-methyl-N6-methyl adenosine 3′-CED phosphoramidite
SKU
HY-154485-Get quote
Category Oligonucleotides
Tags Cancer, Cell Cycle/DNA Damage, Nucleoside Antimetabolite/Analog
Products Details
Product Description
– 5′-O-DMTr-2′-O-methyl-N6-methyl adenosine 3′-CED phosphoramidite is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].
Web ID
– HY-154485
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C42H52N7O7P
References
– [1]Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.
CAS Number
– 2348385-04-4
Molecular Weight
– 797.88
SMILES
– CNC1=NC=NC2=C1N=CN2[C@@H]3O[C@@H]([C@H]([C@H]3OC)OP(N(C(C)C)C(C)C)OCCC#N)COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Nucleoside Antimetabolite/Analog
Pathway
– Cell Cycle/DNA Damage
Product type
– Oligonucleotides
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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