5-LOX-IN-1

$60$450

Products Details

Product Description

– 5-LOX-IN-1 (compound 2b) is an inhibitor of human 5-Lipoxygenase (5-LOX) with an IC50 value of 2.3 μM. 5-LOX-IN-1 can be used for the research of inflammation[1].

Web ID

– HY-148134

Storage Temperature

– -20°C, 3 years (Powder)

Shipping

– Blue Ice

Applications

– COVID-19-immunoregulation

Molecular Formula

– C20H18N2O2S

References

– [1]Sinha S, et al. Design, synthesis and identification of novel substituted 2-amino thiazole analogues as potential anti-inflammatory agents targeting 5-lipoxygenase. Eur J Med Chem. 2018 Oct 5;158:34-50.

CAS Number

– 55040-82-9

Molecular Weight

– 350.43

Compound Purity

– 98.04

SMILES

– O=C(C1=C(C2=CC=CC=C2)N=C(N3CCOCC3)S1)C4=CC=CC=C4

Clinical Information

– No Development Reported

Research Area

– Inflammation/Immunology

Solubility

– DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)

Target

– Lipoxygenase

Pathway

– Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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