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5-Azidomethyl-2’-beta-methyl-2’,3’,5’-tri-O-benzoyluridine
SKU
HY-154462-Get quote
Category Oligonucleotides
Tags Cancer, Cell Cycle/DNA Damage, Nucleoside Antimetabolite/Analog
Products Details
Product Description
– 5-Azidomethyl-2’-beta-methyl-2’,3’,5’-tri-O-benzoyluridine is a thymidine analog. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis[1]. 5-Azidomethyl-2’-beta-methyl-2’,3’,5’-tri-O-benzoyluridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
Web ID
– HY-154462
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C32H27N5O9
References
– [1]Cavanagh BL, et al. Thymidine analogues for tracking DNA synthesis. Molecules. 2011 Sep 15;16(9):7980-93.
CAS Number
– 2305416-08-2
Molecular Weight
– 625.58
SMILES
– O=C(NC(C(CN=[N+]=[N-])=C1)=O)N1[C@@H]2O[C@H](COC(C3=CC=CC=C3)=O)[C@@H](OC(C4=CC=CC=C4)=O)[C@@]2(C)OC(C5=CC=CC=C5)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Nucleoside Antimetabolite/Analog
Pathway
– Cell Cycle/DNA Damage
Product type
– Oligonucleotides
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.