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5-Aminolevulinic acid (hydrochloride)
$55 – $330
Web ID
– HY-N0305
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C5H10ClNO3
Citations
– Adv Sci (Weinh). 2019 Jan 20;6(5):1802057. |Cell Death Dis. 2021 Oct 25;12(11):999.|EMBO Mol Med. 2023 Feb 6;e16959.|Genome Biol. 2022 Dec 15;23(1):259.|Photodiagnosis Photodyn Ther. 2022 Aug 3;103053.|Photodiagnosis Photodyn Ther. 2023 May 21;103612.|bioRxiv. 2023 Jun 3.|J Inorg Biochem. 2023 Jul 24, 112340.|Lasers Med Sci. 2021 Jan 3.|Pharmacol Res. 2021 Jun 1;105701.
References
– [1]Stummer, W., et al., Fluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant glioma: a randomised controlled multicentre phase III trial. Lancet Oncol, 2006. 7(5): p. 392-401.|[2]Eyupoglu, I.Y., et al., Improving the extent of malignant glioma resection by dual intraoperative visualization approach. PLoS One, 2012. 7(9): p. e44885.
CAS Number
– 5451-09-2
Molecular Weight
– 167.59
Compound Purity
– 98.0
SMILES
– O=C(O)CCC(CN)=O.[H]Cl
Clinical Information
– Launched
Research Area
– Metabolic Disease; Cancer
Solubility
– DMSO : 100 mg/mL (ultrasonic)|H2O : 16.67 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Apoptosis;Autophagy;Endogenous Metabolite;Mitophagy
Isoform
– Human Endogenous Metabolite
Pathway
– Apoptosis;Autophagy;Metabolic Enzyme/Protease
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
