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Products Details
Product Description
– 4-Pentynoyl-Val-Ala-PAB-PNP is a cleavable ADC linker, that has been used to synthesis cryptophycin conjugates[1]. 4-Pentynoyl-Val-Ala-PAB-PNP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Web ID
– HY-151740
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C27H30N4O8
References
– [1]Cedric DESSIN, et al. Cryptophycin compounds and conjugates thereof. WO2022175222
CAS Number
– 1956294-76-0
Molecular Weight
– 538.55
SMILES
– C#CCCC(N[C@@H](C(C)C)C(N[C@@H](C)C(NC(C=C1)=CC=C1COC(OC2=CC=C(C=C2)[N+]([O-])=O)=O)=O)=O)=O
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– 10 mM in DMSO
Target
– ADC Linker
Isoform
– Cleavable Linker
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– ADC Related
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
