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4-Methylhistamine

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Product Description

– 4-Methylhistamine is a potent agonist of histamine 4 receptor (H4R). 4-Methylhistamine has the potential for the research of immune-related diseases such as cancer and autoimmune disorders[1][2].

Web ID

– HY-W580721

Shipping

– Room temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C6H11N3

References

– [1]Ahmad SF, et al. Stimulation of the histamine 4 receptor with 4-methylhistamine modulates the effects of chronic stress on the Th1/Th2 cytokine balance. Immunobiology. 2015;220(3):341-349.|[2]Kim CH, et al. Inhibitory Effect of Imiquimod-Induced Psoriasis-Like Skin Inflammation in Mice by Histamine H4 Receptor Agonist 4-Methylhistamine. Scand J Immunol. 2016 Jun;83(6):409-17.

CAS Number

– 36507-31-0

Molecular Weight

– 125.17

SMILES

– NCCC1=C(C)N=CN1

Clinical Information

– No Development Reported

Research Area

– Cancer, Inflammation/Immunology

Solubility

– 10 mM in DMSO

Target

– Histamine Receptor

Pathway

– GPCR/G Protein, Immunology/Inflammation, Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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